Current Trials

Greensboro Clinical Studies

Crohn’s Disease

This is a 12-month study for patients with moderate to severe active CD. Qualified participants will receive study medication or placebo and care related to CD. Compensation for eligible patients is provided.

  • Between the ages of 18 and 80
  • Have a diagnosis of CD or fistulizing CD on lab report
  • Meet medication criteria and other inclusion/exclusion criteria

Diabetic Kidney Disease Trial

This study is for patients who have diabetes and chronic kidney disease.

  • Must be > 18 years old
  • Meet laboratory requirements
  • Not on dialysis
  • Meet other inclusion and exclusion criteria

This is a blinded study. Compensation for participation is provided.

Eczema

Are you struggling with control of your eczema, also known as atopic dermatitis? You may qualify for a research study if you meet the following qualifications:

  • Have moderate to severe eczema or atopic dermatitis.
  • Using topical or other treatments that are not effective.
  • Meet other inclusion and exclusion criteria

Participants will receive fee study medication and care for eczema. Qualified participants may also receive reimbursement for participating in the study.

Erosive Esophagitis

Do you experience severe heartburn or reflux? You may be eligible to participate in this 41 week study to treat a condition called Erosive Esophagitis in which all patients receive active treatment with the goal of healing the esophagitis. You may be eligible to participate if you meet the following criteria:

  • Been diagnosed with Erosive Esophagitis and continue to have symptoms of heartburn or reflux
  • 18 years of age and older
  • Meet other inclusion and exclusion criteria

Qualified participates will receive study medication, endoscopy and care for Erosive Esophagitis at no cost and may be compensated to participate.

Gastroesophageal Reflux Disease (GERD)

Qualified candidates will receive study medication or placebo in addition to related healthcare for GERD. Compensation for eligible patients is provided.

This is an 8 week study for men and women who:

  • Continue to experience reflux while on prescribed and required dosage of GERD medication
  • Agree to having endoscopy procedures performed
  • Meet other inclusion and exclusion criteria

H-Pylori and Erosive Esophagitis

This is a six-month trial being conducted in the Greensboro office. Qualified participants will receive study medication and care related to RA. Compensation for eligible patients is provided. Have you suffered from acid related disorders similar to GERD? This clinical trial is designed for patients who are confirmed on endoscopy to have erosive esophagitis (EE) or may have H. Pylori.

  • Patients must meet all medication requirements
  • Patients must meet other inclusion and exclusion criteria

Irritable Bowel Syndrome

Do you suffer from abdominal pain related to Irritable Bowel Syndrome (IBS)?

This 16 week study will determine the effectiveness of a medication in treating pain associated with Irritable Bowel Syndrome (IBS). You may be eligible to participate if you meet the following requirements:

  • Have Irritable Bowel Syndrome (IBS) with either constipation or diarrhea AND have abdominal pain
  • Between the ages of 18 and 70
  • Meet other inclusion and exclusion criteria

Qualified participants will received study medication and care for Irritable Bowel Syndrome (IBS) at no cost and may be compensated to participate.

Low Testosterone and Cardiovascular Disease

Have you been diagnosed with low testosterone? This is a long-term study to evaluate a topical medication for men with low testosterone between ages 45-80. Patients must:

  • Experienced a cardiovascular event such as a heart attack or stroke or have a blocked artery.
  • Meet laboratory testosterone levels.
  • Meet other inclusion and exclusion criteria.

Qualified participants will receive study medication or placebo and care related to low testosterone. Compensation for eligible patients is provided. This study is being conducted in both the Raleigh and Greensboro.

Osteoarthritis of the Knee

Do you have Osteoarthritis of the knee and continue to struggle with knee pain? This 28 week study is looking for patients with moderate to severe osteoarthritis of the knee who continue to have frequent knee pain despite routine treatment. You may be eligible to participate in this study if you meet the following requirements:

  • Pain in the knee due to Osteoarthritis
  • Never had a knee replacement in the target knee
  • Meet other inclusion and exclusion criteria

Qualified participants will receive study medication and care for osteoarthritis of the knee at no cost and may be compensated to participate.

Ankylosing Spondylitis (Inflammatory Back Pain)

Do you suffer with chronic low back pain and been diagnosed with Ankylosing Spondylitis or Spondyloarthritis as the cause? You may be eligible to participate in this 52 week trial if you have chronic low back pain that is caused by an inflammatory arthritis called Ankylosing Spondylitis. You may also have additional swollen and tender joints associated with this condition and this medication is being studied to determine it’s effectiveness and safety. Qualified participants must meet the following criteria:

  • Have chronic low back pain and stiffness due to a condition called Ankylosing Spondylitis or Spondyloarthritis with or without other joint involvement
  • At least 18 years of age
  • Must meet other inclusion and exclusion criteria

Qualified participants will receive study medication and care for Ankylosing Spondylitis or Spondyloarthritis at no cost and may be compensated to participate.

Psoriatic Arthritis

Do you suffer from arthritis associated with a skin condition called Psoriasis? This study is enrolling patients with active psoriasis skin lesions AND swelling and tenderness of joints who continue to have symptoms despite current treatment. You may be eligible to participate if you meet the following qualifications:

  • Have been diagnosed with Psoriatic Arthritis with tender/swollen joints AND have skin lesions of Psoriasis
  • 18 years of age or older
  • Meet other inclusion and exclusion criteria

Qualified participants will receive study medication and care for Psoriatic Arthritis at no cost and may receive compensation for participation.

Rheumatoid Arthritis

Do you have Rheumatoid Arthritis that is poorly controlled and still have joint tenderness and swelling? You may be eligible to participate if:

  • You have moderate to severe Rheumatoid Arthritis
  • Continue to have swollen and tender joints
  • Must meet other inclusion and exclusion criteria

Qualified patients will receive study medication and care for Rheumatoid Arthritis at no cost and also may be compensated to participate.

Systemic Lupus Erythematosus (SLE)

This is a blinded 14-month study for patients who have SLE (Lupus) and

  • Are at least 18 years of age
  • Are on standard therapies for SLE
  • Continue to experience symptoms from SLE

Patients will receive study medication or placebo as well as healthcare related to SLE. Participation is free and compensation for qualified participants is available.

Raleigh Clinical Studies

Low Testosterone (Hypogonadism) and Cardiovascular Disease

Have you been diagnosed with low testosterone? This is a long-term study to evaluate a topical medication for men with low testosterone between ages 45-80. Patients must:

  • Experienced a cardiovascular event such as a heart attack or stroke or have a blocked artery.
  • Meet laboratory testosterone levels.
  • Meet other inclusion and exclusion criteria.

Qualified participants will receive study medication or placebo and care related to low testosterone. Compensation for eligible patients is provided. This study is being conducted in both the Raleigh and Greensboro.

Cardiology (Greensboro) Clinical Studies

Congestive Heart Failure

This study is for patients with congested heart failure who are:

  • Stable and have CHF
  • Laboratory values within study range
  • Age > 40 years old
  • Meet other inclusion and exclusion criteria

Qualified participants will receive study medication or placebo and care related to CHF. Compensation for eligible patients is provided.

Heart Failure with Reduced Ejection Fraction

This is a long-term study up to 3-5 years and is being conducted at the Greensboro facility. Qualified participants will receive study medication or placebo and care related to CHF. Compensation for eligible patients is provided. This trial is to determine the safety and efficacy of iron therapy using study medication relative to placebo in the treatment of participants in heart failure with a reduced heart function.

Patients must:

  • Have stable CHF
  • Left Ventricular Ejection Fraction < 35%
  • Meet laboratory values for the study
  • Meet other inclusion and exclusion criteria

Stable Angina

This is a 12-month study for patients with chronic stable angina. You may qualify for this study if you have

  • A history of stable angina
  • Documented coronary heart disease such as having an artery blockage or heart attack
  • Meets other inclusion and exclusion criteria

Patients will receive study medication or placebo as well as healthcare related to angina. Participation is free and compensation for qualified participants is available.