Current Trials

Greensboro Clinical Studies

Chronic Kidney Disease Trial

Do you suffer from Chronic Kidney Disease (CKD) or declining kidney function? You may qualify for a research study involving a new medication to treat this condition if you meet the following criteria:

  • Have declining kidney function as evidenced by blood tests
  • Have protein in your urine
  • Meet other inclusion and exclusion criteria

Qualified participants will receive free evaluation and care for their kidney disease, free study medication and may receive reimbursement to participate.

Respiratory Syncytial Virus (RSV) Vaccine Trial

RSV is an important cause of serious respiratory infections in adults aged 60 and older, in immunocompromised individuals and individuals with chronic cardiopulmonary conditions. Come be a part of this exciting research study for a vaccine against this viral illness! You may be eligible if you meet the follow requirements:

  • 60 years old or older
  • Healthy or medical conditions that are stable
  • Meet other inclusion/exclusion criteria

Participation is free, the study vaccine is free and you may be compensated if you meet eligibility criteria and enroll in the study

High Cholesterol

Volunteer for this exciting study for high cholesterol! You may be eligible if you meet the following criteria:

  • Have high cholesterol (bad cholesterol known as LDL and high triglycerides)
  • Currently taking medications to lower your cholesterol
  • Meet other inclusion and exclusion criteria

Qualified participants will receive free study medication and free care for high cholesterol. Participants will also receive compensation for completed study visits.

Meningitis Vaccine Trial

Meningitis is more common in teenagers and young children. The best option to help prevent this is the use of a vaccine against meningitis. This study is looking at how safe a potential new meningitis vaccine is and whether it may act as a booster in people who have already received a vaccine against 4 of the most common types of meningococcal germs that cause meningitis. The study will compare the investigational vaccine with an approved MenACWY vaccine called Menveo. You may be eligible to participate in this study if you meet the following criteria:

  • Are healthy
  • Are 15-25 years of age
  • Received 1 dose of a meningitis vaccine 4-6 years ago.

Participants will be in the study up to 12 months, receive free investigational vaccines and will receive reimbursement to participate.

Colorectal Cancer Screen

Have you been advised to have a colonoscopy as part of your general health and well being as a screening tool for cancer? You may be eligible to participate if

  • You are at least 40 years of age or older
  • Standard of care colonoscopy is scheduled
  • Meet other inclusion and exclusion criteria

Patients will receive healthcare related to colon screening. Participation is free and compensation for qualified participants is available.

Continuous Glucose Monitoring Trial in Type 2 Diabetes Mellitus

Do you have Type 2 Diabetes Mellitus that is not under good control and currently performing fingerstick blood sugars to monitor it? We are currently conducting a clinical trial evaluating a Continuous Glucose Monitoring (CGM) system and it’s impact on your ability to control your blood sugars better. You may be eligible to participate in this study if you meet the following qualifications:

  • A1C is > 7.5%
  • Currently on at least one oral medication for diabetes
  • Not taking insulin
  • Meet other inclusion and exclusion criteria

Compensation for participation is provided

Crohn’s Disease

This is a 12-month study for patients with moderate to severe active CD. Qualified participants will receive study medication or placebo and care related to CD. Compensation for eligible patients is provided.

  • Between the ages of 18 and 80
  • Have a diagnosis of CD or fistulizing CD on lab report
  • Meet medication criteria and other inclusion/exclusion criteria

High Blood Pressure

Volunteer for this exciting study for high blood pressure! You may be able to participate if you meet the following criteria:

  • 18 years old or older
  • Currently have poorly controlled high blood pressure
  • On 2 or more medications for high blood pressure
  • Meet other inclusion/exclusion criteria

Participants will receive study medication, labs and medical care at no cost.

May receive compensation for completed study visits.

High Triglycerides-cholesterol

This 36 week study is for patients with severe hypertriglyceridemia (high triglycerides). Qualified patients will receive study medications at no cost. Compensation for eligible patients is provided.

  • Study candidates must have severely elevated triglyceride levels
  • Study candidates may be on fish oil or statins
  • Must meet other inclusion and exclusion criteria

Qualified patient will receive study medication or placebo and care related to high triglyceridemia. This study is being conducted at our Greensboro location.

Low Testosterone and Cardiovascular Disease

Have you been diagnosed with low testosterone? This is a long-term study to evaluate a topical medication for men with low testosterone between ages 45-80. Patients must:

  • Experienced a cardiovascular event such as a heart attack or stroke or have a blocked artery.
  • Meet laboratory testosterone levels.
  • Meet other inclusion and exclusion criteria.

Qualified participants will receive study medication or placebo and care related to low testosterone. Compensation for eligible patients is provided. This study is being conducted in both the Raleigh and Greensboro.

Oral Insulin in Type 2 Diabetes Mellitus

Do you have Type 2 Diabetes Mellitus and have difficulty controlling your blood sugars?

You may be eligible to participate in this study if you meet the following qualifications:

  • Have Type 2 Diabetes Mellitus AND have elevated blood sugars despite treatment with Metformin alone or with Metformin an up to 2 additional diabetes medications
  • Have not been on insulin for at least the past 6 months
  • Meet other inclusion and exclusion criteria

Qualified participants will receive care for their diabetes at no cost, study medication at no case, and may be paid to participate.

Rheumatoid Arthritis

Do you have Rheumatoid Arthritis that is poorly controlled and still have joint tenderness and swelling? You may be eligible to participate if:

  • You have moderate to severe Rheumatoid Arthritis
  • Continue to have swollen and tender joints
  • Must meet other inclusion and exclusion criteria

Qualified patients will receive study medication and care for Rheumatoid Arthritis at no cost and also may be compensated to participate.

Systemic Lupus Erythematosus (SLE)

A 52 week study for patients with moderate to severe Lupus who continue to have symptoms despite treatment. You may be eligible to participate if you meet the following criteria:

  • 18 years old or older
  • Diagnosed with Active Lupus for at least 24 weeks
  • Currently having breakthrough symptoms of Lupus despite treatment
  • Meet other inclusion/exclusion criteria

Study-related medications, labs and care provided at no cost.

May be compensated for completed study visits.

Raleigh Clinical Studies

Chronic Kidney Disease Trial

Do you suffer from Chronic Kidney Disease (CKD) or declining kidney function? You may qualify for a research study involving a new medication to treat this condition if you meet the following criteria:

  • Have declining kidney function as evidenced by blood tests
  • Have protein in your urine
  • Meet other inclusion and exclusion criteria

Qualified participants will receive free evaluation and care for their kidney disease, free study medication and may receive reimbursement to participate.

Low Testosterone (Hypogonadism) and Cardiovascular Disease

Have you been diagnosed with low testosterone? This is a long-term study to evaluate a topical medication for men with low testosterone between ages 45-80. Patients must:

  • Experienced a cardiovascular event such as a heart attack or stroke or have a blocked artery.
  • Meet laboratory testosterone levels.
  • Meet other inclusion and exclusion criteria.

Qualified participants will receive study medication or placebo and care related to low testosterone. Compensation for eligible patients is provided. This study is being conducted in both the Raleigh and Greensboro.

Cardiology (Greensboro) Clinical Studies

Cardiovascular Risk Reduction Trial

Do you have a history of a heart attack, stroke, and/or peripheral artery disease? You may be eligible for our research study to evaluate whether the study medication will reduce the risk of future events. You may be eligible if you meet the following criteria:

  • Be between the ages of 18 and 80
  • Must be receiving treatment to lower cholesterol
  • Have a history of a heart attack, stroke or peripheral arterial disease
  • Meet other inclusion and exclusion criteria

Participants will receive free cardiovascular risk evaluation, free study medication and may be compensated to participate.

Heart Attack Trial

Have you recently experienced a heart attack? We are currently conducting a research study in patients who have recently had a heart attack and are at risk for developing heart failure. You may be eligible for the study if you meet the following criteria:

  • Had a heart attack and it is within 14 days of your hospitalization
  • Have risk factors for developing heart failure
  • Meet other inclusion/exclusion criteria

Participation is free as is study medication and you may be compensated for your participation

Heart Failure with Reduced Ejection Fraction

This is a long-term study up to 3-5 years and is being conducted at the Greensboro facility. Qualified participants will receive study medication or placebo and care related to CHF. Compensation for eligible patients is provided. This trial is to determine the safety and efficacy of iron therapy using study medication relative to placebo in the treatment of participants in heart failure with a reduced heart function.

Patients must:

  • Have stable CHF
  • Left Ventricular Ejection Fraction < 35%
  • Meet laboratory values for the study
  • Meet other inclusion and exclusion criteria

Stable Angina

This is a 12-month study for patients with chronic stable angina. You may qualify for this study if you have

  • A history of stable angina
  • Documented coronary heart disease such as having an artery blockage or heart attack
  • Meets other inclusion and exclusion criteria

Patients will receive study medication or placebo as well as healthcare related to angina. Participation is free and compensation for qualified participants is available.

Urology (Greensboro) Clinical Studies

Overactive Bladder

Do you experience overactive bladder or urinary incontinence?  We are conducting an exciting clinical trial involving a device to treat overactive bladder or urinary incontinence. You may be eligible to participate if you meet the following criteria:

  • 18 years old or older
  • Urinary incontinence that is not responding to medication and/or non-medication therapy or unable to take medication for urinary incontinence
  • Have at least 3 episodes of urinary incontinence in a 72 hour period
  • Meet other inclusion and exclusion criteria

Eligible participants will receive free evaluation and care of overactive bladder or urinary incontinence, free study medication and may receive reimbursement to participate.

Prostate Cancer Trial

Have you been recently diagnosed with prostate cancer? You may be a candidate for an exciting clinical drug trial evaluating a new medication for the treatment of prostate cancer if you meet the following requirements:

  • 18 years old or older
  • Recently diagnosed with prostate cancer and at high risk for spread
  • Meet other inclusion/exclusion criteria

Participants who enroll in the trial will receive free medical care of prostate cancer, free study medication and compensation for participation.